VIP

VIP is the synthetic form of vasoactive intestinal peptide, a naturally occurring 28-amino-acid peptide first isolated from porcine small intestine in 1970. The amidated human peptide has the molecular formula C147H238N44O42S, a molecular weight of 3,325.8 g/mol excluding salt counterions, and is identified by CAS number 40077-57-4. The peptide is notable for activating VPAC1 and VPAC2 receptors—cell-surface proteins involved in signaling through cyclic AMP. VIP is classified as a peptide hormone and neurotransmitter and is studied for its roles in vascular tone, gastrointestinal function, and immune signaling.

Supplied as one individual 10 mg vial. Each purchase quantity refers to one individual vial, not a supplier box.

Chemical identifiers refer to the stated reference form; salt counterions can change formula weight. Follow the supplied material’s documentation for storage and handling. Cited research is not a batch analysis of this product.

For laboratory research use only. Not for human or animal use.

Research and chemical references

• Original research
• Sigma-Aldrich
• Product specification