GHK-Cu

GHK-Cu, also known as copper tripeptide-1, is a naturally occurring tripeptide composed of the amino acids glycine, L-histidine, and L-lysine, complexed with a divalent copper ion (Cu²⁺). First identified in human plasma in the 1970s, it functions as a high-affinity copper-binding peptide and is found in saliva, urine, and other tissues. The peptide sequence (glycyl-L-histidyl-L-lysine) forms a stable complex with copper through coordination at the histidine residue and terminal amine groups, facilitating its biological activity. For the neutral 1:1 complex represented as C14H22CuN6O4, the calculated molecular weight is approximately 401.9 g/mol, excluding counterions. Salt and coordination representations can differ: the linked GHK-Cu monoacetate reference is C14H22CuN6O4·C2H4O2, 462.0 g/mol. CAS 49557-75-7 identifies the uncomplexed GHK peptide and should not be presented as a unique identifier for this supplied copper complex.

Available individual vial sizes: 50mg, 100mg. Each purchase quantity refers to one individual vial, not a supplier box.

Chemical identifiers refer to the stated reference form; salt counterions can change formula weight. Follow the supplied material’s documentation for storage and handling. Cited research is not a batch analysis of this product.

For laboratory research use only. Not for human or animal use.

Research and chemical references

• GHK-Cu acetate reference; distinguishes complex and counterion mass
• Uncomplexed GHK reference — CAS 49557-75-7
• Original GHK human-serum report (1973)